Dr. Peipert is the Principal Investigator in these studies currently enrolling pateints:

A Randomized, Placebo-Controlled Phase II Study of Multiple, Intravaginally Administered, Dosing Regimens of 851B Gel for the Treatment of Cervical High Risk HPV Infection.

Purpose: To evaluate the safety and effectiveness of multiple applications of 851B gel as  compared to placebo gel to assess the clearance of the HPV infection and abnormal cells of the cervix.   

Patient Selection: Women, who are 18-40 years old, are of childbearing potential, has a Pap test interpretation of either LSIL or ASC-US, able to give informed consent, and willing to comply with protocol follow-up for 26 months.

The contraceptive CHOICE program

Purpose:  To remove the financial barriers to obtaining contraception, including the most effective (and expensive) methods.  We will study satisfaction and continuation rates, as well as reasoning behind discontinuation.

Patient Selection:  Women, ages 13-45, who are about to initiate contraception of any kind and are willing to be followed for three years.

TO LEARN MORE ABOUT THESE STUDIES CALL 314-747-0800

Dr. Merritt is the Principal Investigator in these studies currently enrolling patients:

MENSTRUAL CRAMPING IN TEENS
“A Randomized Multicenter, Double-Blind Exploratory Study to Evaluate the Efficacy of an Extended cycle Combination Oral Contraceptive Compared to Placebo for the Treatment of Cyclic Pain in Adolescents.”
 
We are currently recruiting adolescent patients for the treatment of monthly menstrual pain.  Parental consent is required for this study if under age 18 years.  Patients will be evaluated and then randomized into a placebo group or treatment group.  The treatment is a low dose oral contraceptive pill. Patients are eligible to receive a stipend if they qualify and fulfill the requirements of the study. Interested patients should contact Dr. Merritt’s nurse at 314-747-1413 for more information.  Please leave your contact information on the answering machine which operates at all hours.

You must

• Be a healthy, adolescent female, under 18 years and not sexually active
• Have moderate to severe pelvic pain during your period
• Have not been on oral contraceptive for three months prior to starting the study

This study will last seven months with five study visits.  Procedures include a physical exam, ultrasound, blood and urine tests, and study drug.  Volunteers may experience relief from their pelvic pain.  Up to $300 is provided for time and effort.

ABSENT MENSTRUAL PERIODS (AGES 18-50)
A Phase II, Multicenter, Double-Blind, Randomized, Placebo-Controlled Study to Evaluate Induction of Withdrawal Bleeding After Administration of Oral Micronized Progesterone in Women with Secondary Amenorrhea”
This is a clinical trial to bring on menstrual bleeding in non-pregnant women who may have stopped having their period for any number of reasons using a natural form of progesterone.  Interested patients should contact Dr. Merritt’s nurse at 314-747-1413 for more information.  Please leave your contact information on the answering machine which operates at all hours.

You must

• Be healthy, ages 18-50, and not pregnant
• Not have had a period in the last 50 days
• Have normal estrogen levels
• Not use hormonal forms of birth control during the study

This study will last about one month, with a screening visit and 4 study visits.  Procedures include a physical and pelvic exam, blood and urine tests, medical history, and menstrual diary.  Volunteers may get a period from the progesterone.  Up to $200 is provided for time and effort.

HEAVY MENSTRUAL BLEEDING (AGES 18-49)
A 12 Month, Open Label, Multicenter Study to Evaluate the Safety of a Oral Dose of a New Modified-Release Non-hormonal Formulation Administered Three Times Daily as Needed for up to 5 Days during the Menstrual Cycle in Women, with Heavy Menstrual Bleeding Associated with Menorrhagia
This study is for women who experience heavy menstrual bleeding on 2 to 5 days of their regular menstrual cycle.

You must

• Be a generally healthy woman between the ages of 18 and 49 years
• Have regular menstrual cycles with heavy bleeding
• Not have any other bleeding disorder

If you qualify, you will receive study drug and study related procedures, physicals exams, electrocardiogram, eye examinations and laboratory tests at not cost.  You will also receive compensation for your time and travel.

TO LEARN MORE ABOUT THESE STUDIES CALL 314-747-1413